Pan Li, Ming Zhou, Qingyang Zhao, Weilong Wu, Xinquan Hu, Xiu-Qin Dong, and Xumu Zhang . Access scientific knowledge from anywhere. Azim Ziyaei Halimehjani, Irishi N. N. Namboothiri, Seyyed Emad Hooshmand. Anticonvulsant activity of indanylspirosuccinimide mannich bases. Banyak senyawa hasil kondensasi ini yang dilaporkan memiliki bioaktivitas seperti anti-inflamasi, antikanker, antimalaria, antibakteri, antifungal, antikonvulsan, antitubercular, analgesik dan anti-HIV, ... On the other hand, exhaustive review articles have shown that Mannich bases have vast pharmacological profiles with a wide range of therapeutic applications. The … Qiong Yu, Zhixin Wang, Bo Wu, Hongwei Yang, Xuehai Ju, Chunxu Lu, Guangbin Cheng. Cristina Izquierdo, Francisco Esteban, José Luis García Ruano, Alberto Fraile, and José Alemán . Asymmetric Organocatalyzed Aza‐Henry Reaction of Hydrazones: Experimental and Computational Studies. Toshihiro Isobe, Atsuki Kato, Takeshi Oriyama. Yi Peng, Yan-Hui Fan, Si-Yuan Li, Bin Li, Jing Xue. α
Jakub Iwanejko, Elżbieta Wojaczyńska, Jacek Wojaczyński, Julia Bąkowicz. Review Article. Organic & Biomolecular Chemistry 2018, 16 (9) , 1457-1460. The antidepressant fluoxetine can be accumulated in sewage effluents and it could pose a hazard to infauna inhabiting surrounding areas. Learn more. M. Jesús García-Muñoz, Haythem K. Dema, Francisco Foubelo, Miguel Yus. Nucleophilic ring opening of aziridines with amines under catalyst- and solvent-free conditions. Reactions of Aldehydes and Ketones and Their Derivatives. This review provides an overview of asymmetric Mannich reactions in recent years under different organocatalytic systems, including: chiral amines, chiral bifunctional thiourea, chiral Brønsted acids and other chiral organocatalytic systems. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. e results, fact that the presence of morpholine ring in heterocyclic, molecules increases the antimicrobial activity [, namide were synthesized with secondary amines like mefe-, inammatory activity was studied by hind paw oedema, than Mannich bases of mefenamic acid (MNM). BIUF was found t, active than TNTUF due to the presence of two N ato, the benzimidazole adjoined with amide group [, A series of novel Mannich bases of ,,-oxadiazole, synthesized. Sure Siva Prasad, Soundararasu Senthilkumar, Akriti Srivastava, and Sundarababu Baskaran . Nearly all the synthesized compounds exhibited antimicrobial activity against gram positive and gram negative bacteria at 500 μg concentration. Nitro-Mannich reaction and intramolecular 1,3-dipolar cycloaddition route to acylpyrrolidinones: Synthesis of a tetramic acid and (+)-laccarin. Among the synthesized compounds RS II showed moderate antibacterial activity against B. subtilis, RS I, RS II, RS III and RS VI showed moderate antibacterial activity against P. aeruginosa, RS V and RS VI showed good anti fungal activity against P. notatum. Few of these Mannish bases have been evaluated for their possible antifungal and antibacterial activity. Michael G. Papanikolaou, Sofia Hadjithoma, Dimitra S. Chatzikypraiou, Dionysios Papaioannou, Chryssoula Drouza, Athanassios C. Tsipis, Haralampos N. Miras, Anastasios D. Keramidas, Themistoklis A. Kabanos. the nitro-Mannich reaction and
e examples of clinicall. A series of 3-substituted-4-(5-nitro-2-furfurylidene)amino-5-mercapto-1,2,4-triazoles 3 and their Mannich bases have been synthesized. Asymmetric Aza‐Henry Reaction of Indolenines Mediated by a Cinchona‐Alkaloid‐Thiourea Organocatalyst. Palladium triggered diene formation from nitro allylic compounds: a versatile entry into naphthalene derivatives. Number of times cited according to CrossRef: Applications of Selenonium Cations as Lewis Acids in Organocatalytic Reactions. The literature studies enlighten the fact that Mannich bases are very reactive and recognized to possess potent diverse activities like anti-inflammatory, anticancer, antifilarial, antibacterial, antifungal, anticonvulsant, anthelmintic, antitubercular, analgesic, anti-HIV, antimalarial, antipsychotic, antiviral activities and so forth. N
Structural diversity of copper(II) amino alcoholate complexes. Other amide linkages havd been produced through the reaction of succinyl chloride with two moles of these drugs to afford 1,3-dicarbohydrazides succinyl derivatives (L22-L24).