Adriano S. Vieira, Fernando P. Ferreira, Pedro F. Fiorante, Rafael C. Guadagnin, Hélio A. Stefani. The polymer with KB was used for the detection of SA using CV, DPV and CA. Total Synthesis of (−)-Sessilifoliamide J. Ramesh Mudududdla, Shreyans K. Jain, Jaideep B. Bharate, Ajai P. Gupta, Baldev Singh, Ram A. Vishwakarma, and Sandip B. Bharate . Information about how to use the RightsLink permission system can be found at Due to the number of excellent review articles of the classical tricomponent Mannich reaction and to the lack of significant new methodology (see, however, Section 4.1.1.5), only a brief overview is given. With 4-dimethylamino-methylcinnamate or -cinnamyl aldehyde and α-haloamines amino-methylation takes place under formation of 6 and 7. aldehydes catalyzed by protected diarylprolinols are presented. The use of zinc tetrafluoroborate as a catalyst in Mannich-type addition of silyl enol ethers to aldimines in aqueous THF provides β-amino ketones or β-amino esters in high yields. For permission to reproduce, republish and Gloria Rassu,, Luciana Auzzas,, Vincenzo Zambrano,, Paola Burreddu,, Luigi Pinna,, Lucia Battistini,, Franca Zanardi, and. Some Reactions of 3-Chloroisoindolium Salts with Nucleophiles: Access to Isoindole Derivatives and Ellipticine Analogues as Potential Antiviral Agents. Furthermore, in contrast to most asymmetric Mannich-type reactions, either syn- or anti-adducts were stereospecifically obtained from (E)- or (Z)-silicon enolates in the present reaction (Entries 3 and 4). K. C. Nicolaou, Dionisios Vourloumis, Nicolas Winssinger, Phil S. Baran. Mode of activation by organocatalyst. Please reconnect. The chronoamperometry showed linear range between 0.5 and 4.5 μM salicylic acid with LOD of 0.18 and 0.12 μM with sensitivity of 1.7788 and 8.8245 μA μM−1 cm−2 at GCE/poly(CoTAPOPMPPc) and GCE/KB-poly(CoTAPOPMPPc) electrodes respectively. Mannich cyclizations are also successful when the carbonyl participant is masked as an acetal or enol ether. The iminium derivative of the aldehyde is the acceptor in the reaction. You have to login with your ACS ID befor you can login with your Mendeley account. system. However, intramolecular Mannich cyclization was accomplished in 52% yield at low temperature by treatment of the bicyclic trimethylsilyl enol ether (30) with 1.1 equiv. http://pubs.acs.org/page/copyright/permissions.html, https://doi.org/10.1021/acs.orglett.0c02697, https://doi.org/10.1021/acs.orglett.9b00521, https://doi.org/10.1021/acs.orglett.8b03371, https://doi.org/10.1021/acs.orglett.6b01712, https://doi.org/10.1007/s11164-013-1378-7, https://doi.org/10.1016/j.tet.2013.03.104, https://doi.org/10.1016/B978-0-12-408100-0.00003-3, https://doi.org/10.1016/j.tet.2011.11.080, https://doi.org/10.1002/9780470638859.conrr409, https://doi.org/10.1016/j.tet.2008.02.006, https://doi.org/10.1002/047084289X.rt327.pub2, https://doi.org/10.1016/B978-008044992-0.00306-0, https://doi.org/10.1016/j.tetlet.2005.10.163, https://doi.org/10.1016/S1099-4831(05)62002-0, https://doi.org/10.1016/S0040-4039(02)02535-2, https://doi.org/10.1016/S0040-4039(01)02052-4, https://doi.org/10.1002/1521-3765(20011001)7:19<4107::AID-CHEM4107>3.0.CO;2-K, https://doi.org/10.1016/S0040-4020(01)00035-7, https://doi.org/10.1016/S0040-4039(00)00625-0, https://doi.org/10.1002/(SICI)1521-3757(20000103)112:1<46::AID-ANGE46>3.0.CO;2-P, https://doi.org/10.1016/S0040-4039(99)01939-5, https://doi.org/10.1016/S0040-4020(99)00452-4, https://doi.org/10.1002/(SICI)1099-0690(199906)1999:6<1395::AID-EJOC1395>3.0.CO;2-T, https://doi.org/10.1016/S0957-4166(99)00051-8, https://doi.org/10.1016/S1874-5148(98)80006-7, https://doi.org/10.1016/S0166-1280(98)00282-6, https://doi.org/10.1016/S0166-1280(98)00146-8, https://doi.org/10.1002/(SICI)1521-3757(19980420)110:8<1096::AID-ANGE1096>3.0.CO;2-Z, https://doi.org/10.1016/S0040-4020(97)10152-1, https://doi.org/10.1016/S0040-4039(97)10080-6, https://doi.org/10.1016/S0957-4166(97)00431-X, https://doi.org/10.1016/S0960-894X(96)00275-2.